Duration of Treatmentusually takes 10 hours

Days of StayUsually 21 days in the hospital and 30 days outside the hospital.

AnesthesiaGeneral anaesthesia.

CostOn Request

What is Liver Transplant Surgery?

Liver transplant is a surgical procedure that removes a liver, who have an end-stage liver failure that can't be controlled by using other treatments for liver cancer and transplant with a healthy donor liver. Most people who have had liver transplants go on to lead perfectly normal lives. Every year about more than 8000 liver transplants is performed in the United States and about  1400 in India.

Liver failure has many causes, including:

  • Liver cirrhosis
  • Biliary duct atresia
  • Genetic diseases
  • Hepatitis B and C.
  • Alcoholic liver disease
  • Cystic fibrosis
  • Hemochromatosis
  • Primary biliary cirrhosis        

There are three types of liver transplantation technique include:

  • Orthotopic transplantation: In which the diseased liver is removed and the transplant with a healthy donor liver.
  • Heterotrophic transplantation: In which the recipient's liver is left in place and the addition of a donor liver at another site.
  • Reduced-size liver transplantation: In which a portion of healthy donor (adult)  liver is used for an infant or small child.

There are two types of liver transplant donor:

  • Cadaver-donor ( brain dead donor)
  • Living donor(from both related and unrelated donors)

Liver transplant surgery signs include:

  • Jaundice
  • Itching
  • Dark yellow coloured urine
  • Gray- or clay-coloured bowel movements
  • Ascites - An abnormal buildup of fluid in the abdomen
  • Vomiting of blood
  • Blood in the stool
  • Tendency to bleed

Liver transplant surgery risk factor includes:-

  • Risks of anaesthesia 
  • Temporary dizziness
  • Bile duct complications,( bile duct leaks )
  • Bleeding
  • Blood clots
  • Failure of donated liver
  • Infection
  • Rejection of liver
  • Mental confusion or seizures

The donor and recipient should be in the ABO blood group and crossmatch (human leukocyte antigen -- HLA) compatible. Both should go for some Specific tests, procedures and consultations

Recipient Evaluation:

  • The recipient should go for blood investigations HBsAg, Anti HCV, HIV I & II, CBC / Hemogram, Liver Function Tests (LFT), Urea, Creatinine, Sodium, Potassium, P time / INR, AFP
  • A good quality triple phase CT angiography of the liver ( It is safe to do this tests in those who have normal urea, creatinine levels and no contrast allergy )
  • A recent Upper GI endoscopy report
  • A few more tests (Stress Echo, PA pressure measurements, PFT, ABG) which will determine the patient’s fitness to undergo such a major operation.
  • The need for a liver transplant will be re-assessed and confirmed once the patient reaches our centre.

Donor Evaluation

  • The donor must be a relative. He must be willing and happy to donate part of his liver purely for altruistic reasons.
  • He or she must preferably be between 18 and 45 years of age, healthy, fit and of a compatible / matching blood group :

    Patient blood group             Matching donor groups       

    A+ or A-                                   A+ / A- /O+ / O-         
    B+ or B-                                   B+ / B- / O+ / O-    
    AB+ or AB -                            Any blood group 
     

Reports:

  • Level I: Blood group
    HBsAg, Anti HCV, HIV I & II, CBC / Hemogram, LFT, Urea, Creatinine, P time / INR, HbA1c,  After 14 hr Fasting, Lipid profile and Serum T3, T4, TSH.
  • If these are okay, proceed to Level II
    Level II: A good quality Triple-phase CT Liver Angio ( donor protocol )

 

Surgery Evaluation

The patient and Donor will require undergoing some pre-operative investigation in order to meet the surgical requirements.

The evaluation includes:

  1. Mental health evaluation (Psychiatrist or Psychologist).
  2. Blood and Diagnostic tests.( Blood test, CT Scan, Echo, X-ray )
  3. Complete health evaluation. ( Eye, Heart, Dental )
  4. The patient and Donor are required to go for PSC ( Pre-surgery check-up )  to do some blood test, ECG and ECH for Cardiac check-up and urine tests to know he /she is fit for surgery or not.
  5. Before the operation patient will be asked to sign a consent form, which gives permission to the surgeon to proceed with the treatment.
  6. The doctor should be informed about any medication that the patient may be taking.
  7. The patient is admitted to the hospital on the same days before the procedures and advised to remain empty stomach/Fasting.
  8. Thinners medicines have to stop before ten days of surgery.

Before surgery, the Liver transplant surgeon and anaesthesia will guide you about benefits and risk factor of Liver transplant surgery.

Step 1 – Anesthesia: Liver transplant surgery takes 10 hours depending upon the procedures by giving local or general anaesthesia to relieve pain.

Step 2 – The incision: The Liver transplant surgeon makes a long incision (cut) into the abdomen to access the liver. The location and size of incision vary according to the surgeon's approach and patient’s anatomy. During surgery, the surgical team monitors patient heart rate, blood pressure and blood oxygen level throughout the procedure. The surgeon visually inspects the donor’s liver before implanting it.

The surgeon disconnects the liver's blood supply and the bile ducts after that they remove the diseased liver. The donor's liver is placed in the patient’s body and blood vessels and bile ducts are then connected to the recipient's arteries and veins. During surgery, the patient’s damaged liver and gallbladder will be removed.

Step 3 – Closing the incisions: The Liver transplant surgeon flaps the skin after the surgery with the help of Sutures, skin adhesives, tapes or clips that close the skin incisions.

  • The doctor will give complete information about post care of surgery, regarding recovery; proper caring of incisions, taking medications and managing.
  • Stitches or staples will be removed after 15 days of surgery. 
  • Patients are allowed to stand and walk using a walking after 3 to 5 days of the surgery
  • If a drain was inserted in lower abdomen during surgery to help with fluid removal, it will remove after 10 to 15 days of surgery.
  • In some cases, if the drain was not removed after 10 days of surgery, patients have to follow-up with some investigation like (bilirubin of drain/ ultrasound) or stent will be advised.
  • The patient needs to take anti-rejection medication lifelong and be monitored regularly with a blood test, its help keep your immune system from attacking and rejecting your new liver.
  • The patient may also require vitamins and calcium and other mineral supplements.

 

The success rate of liver transplantation depends on patient condition, donor organ and surgeon experience. Kidneys from living donors generally last longer than cadaver donor. Sometimes due to the rejection of kidney also cause of unsuccessful. The success rate is more than 90%.

  • Are you board-certified liver transplant surgeon?
  • How many years’ experience of you has in this field?
  • How many surgeries are you doing every day?
  • Does your hospital certify to perform these types of surgery?
  • Am I a good patient for you to this procedure?
  • How long does a transplanted liver last on average?
  • What are the signs and symptoms of liver rejection?
  • Let me know success rates and how long time will take for recovery?
  • What treatment plan do you recommend and Why?
  • What are the advantages and disadvantages of surgery?
  • How should I prepare for this surgery?
  • How long I have to stay in the hospital and outside the hospital?
  • When can I go for normal activities, including exercise?
  • Do I have stitches, staples, and/or bandages?
  • Do I have a scar or other permanent effects from the surgery?
  • Do I need to go another surgery in the future?
  • Do I need any follow-up appointments or tests after my surgery?

 

 

Top Doctors

Top Hospitals

LIVER TRANSPLANT SURGERY

Duration of Treatmentusually takes 10 hours

Days of StayUsually 21 days in the hospital and 30 days outside the hospital.

AnesthesiaGeneral anaesthesia.

CostOn Request

What is Liver Transplant Surgery?

Liver transplant is a surgical procedure that removes a liver, who have an end-stage liver failure that can't be controlled by using other treatments for liver cancer and transplant with a healthy donor liver. Most people who have had liver transplants go on to lead perfectly normal lives. Every year about more than 8000 liver transplants is performed in the United States and about  1400 in India.

Liver failure has many causes, including:

  • Liver cirrhosis
  • Biliary duct atresia
  • Genetic diseases
  • Hepatitis B and C.
  • Alcoholic liver disease
  • Cystic fibrosis
  • Hemochromatosis
  • Primary biliary cirrhosis        

There are three types of liver transplantation technique include:

  • Orthotopic transplantation: In which the diseased liver is removed and the transplant with a healthy donor liver.
  • Heterotrophic transplantation: In which the recipient's liver is left in place and the addition of a donor liver at another site.
  • Reduced-size liver transplantation: In which a portion of healthy donor (adult)  liver is used for an infant or small child.

There are two types of liver transplant donor:

  • Cadaver-donor ( brain dead donor)
  • Living donor(from both related and unrelated donors)

symptoms

Liver transplant surgery signs include:

  • Jaundice
  • Itching
  • Dark yellow coloured urine
  • Gray- or clay-coloured bowel movements
  • Ascites - An abnormal buildup of fluid in the abdomen
  • Vomiting of blood
  • Blood in the stool
  • Tendency to bleed

risk factors

Liver transplant surgery risk factor includes:-

  • Risks of anaesthesia 
  • Temporary dizziness
  • Bile duct complications,( bile duct leaks )
  • Bleeding
  • Blood clots
  • Failure of donated liver
  • Infection
  • Rejection of liver
  • Mental confusion or seizures

preparation

The donor and recipient should be in the ABO blood group and crossmatch (human leukocyte antigen -- HLA) compatible. Both should go for some Specific tests, procedures and consultations

Recipient Evaluation:

  • The recipient should go for blood investigations HBsAg, Anti HCV, HIV I & II, CBC / Hemogram, Liver Function Tests (LFT), Urea, Creatinine, Sodium, Potassium, P time / INR, AFP
  • A good quality triple phase CT angiography of the liver ( It is safe to do this tests in those who have normal urea, creatinine levels and no contrast allergy )
  • A recent Upper GI endoscopy report
  • A few more tests (Stress Echo, PA pressure measurements, PFT, ABG) which will determine the patient’s fitness to undergo such a major operation.
  • The need for a liver transplant will be re-assessed and confirmed once the patient reaches our centre.

Donor Evaluation

  • The donor must be a relative. He must be willing and happy to donate part of his liver purely for altruistic reasons.
  • He or she must preferably be between 18 and 45 years of age, healthy, fit and of a compatible / matching blood group :

    Patient blood group             Matching donor groups       

    A+ or A-                                   A+ / A- /O+ / O-         
    B+ or B-                                   B+ / B- / O+ / O-    
    AB+ or AB -                            Any blood group 
     

Reports:

  • Level I: Blood group
    HBsAg, Anti HCV, HIV I & II, CBC / Hemogram, LFT, Urea, Creatinine, P time / INR, HbA1c,  After 14 hr Fasting, Lipid profile and Serum T3, T4, TSH.
  • If these are okay, proceed to Level II
    Level II: A good quality Triple-phase CT Liver Angio ( donor protocol )

 

Surgery Evaluation

The patient and Donor will require undergoing some pre-operative investigation in order to meet the surgical requirements.

The evaluation includes:

  1. Mental health evaluation (Psychiatrist or Psychologist).
  2. Blood and Diagnostic tests.( Blood test, CT Scan, Echo, X-ray )
  3. Complete health evaluation. ( Eye, Heart, Dental )
  4. The patient and Donor are required to go for PSC ( Pre-surgery check-up )  to do some blood test, ECG and ECH for Cardiac check-up and urine tests to know he /she is fit for surgery or not.
  5. Before the operation patient will be asked to sign a consent form, which gives permission to the surgeon to proceed with the treatment.
  6. The doctor should be informed about any medication that the patient may be taking.
  7. The patient is admitted to the hospital on the same days before the procedures and advised to remain empty stomach/Fasting.
  8. Thinners medicines have to stop before ten days of surgery.

procedure

Before surgery, the Liver transplant surgeon and anaesthesia will guide you about benefits and risk factor of Liver transplant surgery.

Step 1 – Anesthesia: Liver transplant surgery takes 10 hours depending upon the procedures by giving local or general anaesthesia to relieve pain.

Step 2 – The incision: The Liver transplant surgeon makes a long incision (cut) into the abdomen to access the liver. The location and size of incision vary according to the surgeon's approach and patient’s anatomy. During surgery, the surgical team monitors patient heart rate, blood pressure and blood oxygen level throughout the procedure. The surgeon visually inspects the donor’s liver before implanting it.

The surgeon disconnects the liver's blood supply and the bile ducts after that they remove the diseased liver. The donor's liver is placed in the patient’s body and blood vessels and bile ducts are then connected to the recipient's arteries and veins. During surgery, the patient’s damaged liver and gallbladder will be removed.

Step 3 – Closing the incisions: The Liver transplant surgeon flaps the skin after the surgery with the help of Sutures, skin adhesives, tapes or clips that close the skin incisions.

post procedure

  • The doctor will give complete information about post care of surgery, regarding recovery; proper caring of incisions, taking medications and managing.
  • Stitches or staples will be removed after 15 days of surgery. 
  • Patients are allowed to stand and walk using a walking after 3 to 5 days of the surgery
  • If a drain was inserted in lower abdomen during surgery to help with fluid removal, it will remove after 10 to 15 days of surgery.
  • In some cases, if the drain was not removed after 10 days of surgery, patients have to follow-up with some investigation like (bilirubin of drain/ ultrasound) or stent will be advised.
  • The patient needs to take anti-rejection medication lifelong and be monitored regularly with a blood test, its help keep your immune system from attacking and rejecting your new liver.
  • The patient may also require vitamins and calcium and other mineral supplements.

 

success rate

The success rate of liver transplantation depends on patient condition, donor organ and surgeon experience. Kidneys from living donors generally last longer than cadaver donor. Sometimes due to the rejection of kidney also cause of unsuccessful. The success rate is more than 90%.

faqs from doctor

  • Are you board-certified liver transplant surgeon?
  • How many years’ experience of you has in this field?
  • How many surgeries are you doing every day?
  • Does your hospital certify to perform these types of surgery?
  • Am I a good patient for you to this procedure?
  • How long does a transplanted liver last on average?
  • What are the signs and symptoms of liver rejection?
  • Let me know success rates and how long time will take for recovery?
  • What treatment plan do you recommend and Why?
  • What are the advantages and disadvantages of surgery?
  • How should I prepare for this surgery?
  • How long I have to stay in the hospital and outside the hospital?
  • When can I go for normal activities, including exercise?
  • Do I have stitches, staples, and/or bandages?
  • Do I have a scar or other permanent effects from the surgery?
  • Do I need to go another surgery in the future?
  • Do I need any follow-up appointments or tests after my surgery?

 

 

Top Doctors

Top Hospitals

share